Hexarelin Acetate CAS:140703-51-1

Molecular Formula: C47H58N12O6 Molecular Weight: 887.04 Purity (HPLC): 98.0% Single Impurity (HPLC): 0.5%max Amino Acid Composition: about10% of theoretical Peptide Content (N%): 80.0%min. Water Content(Karl Fischer): 8.0%max. Acetate Content(HPIC): 10.0%max. Specific Rotation (20/D): -55.0~-65.0 degree(c=1 1%HAc) MS(ESI): Consistent Mass Balance: 95.0~105.0% Appearance: White powder Description: Hexarelin Indications: Hexarelin (HEX) is a peptide GH secretagogue, structurally similar to GHRP-6, in the grow factor family which stimulates the release of grow hormone (GH). It can be used medically to treat GH deficiency. Hexarelin is a good all purpose anabolic. Also, since we know that IGF and GH use produces a shutdown of your endogenous levels of those hormones, Hexarelin also seems very useful for "GH-PCT" or "IGF-PCT", as it can help restore your natural levels of those hormones after a cycle of them. Ghrelin is an appetite-regulating factor secreted from peripheral organs that is involved in regulation of energy homoeostasis via binding to the receptor resulting in the secretion of growth hormone by the pituitary gland. The pathway activated by binding of ghrelin to the growth hormone secretagogue receptor, GHSR1a, regulates the activation of the downstream mitogen-activated protein kinase, Akt, nitric oxide synthase, and AMPK cascades in different cellular systems. One of the important features of GHSR1a displays constitutive activity possessing basal activity in the absence of an agonist, resulting in a high degree of receptor internalization as well as of signaling activity.Inverse agonists for the ghrelin receptor could be particularly interesting for the treatment of obesity.This activity seems to provide a tonic signal required for the development of normal height, probably through an effect on the GH axis.